Description
Isocitrate dehydrogenase technical support, bulk quantities and aliquoting are available.
Isocitrate dehydrogenase is an enzyme that participates in the citric acid cycle. It catalyzes the third step of the cycle: the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (a-ketoglutarate) and CO2 while converting NAD+ to NADH. This is a two-step process which involves oxidation of isocitrate (a secondary alcohol) to oxalosuccinate (a ketone), followed by the decarboxylation of the carboxyl group beta to the ketone, forming alpha-ketoglutarate